The Central African Republic has been strongly affected by the human immunodeficiency virus (HIV) epidemic. Although itself sparsely populated, the republic borders five other African countries and is crossed by the trans-African highway, which connects West and Central Africa with East Africa. Wide genetic variation reported among HIV-1 subtypes (on the basis of small numbers of samples) suggests multiple introductions of HIV into the republic. However, except in small studies and unpublished reports, the distribution and serologic reactivities of HIV within the Central African Republic have not been characterized.
The Central African Republic has been strongly affected by the human immunodeficiency virus (HIV) epidemic. Although itself sparsely populated, the republic borders five other African countries and is crossed by the trans-African highway, which connects West and Central Africa with East Africa. Wide genetic variation reported among HIV-1 subtypes (on the basis of small numbers of samples) suggests multiple introductions of HIV into the republic. However, except in small studies and unpublished reports, the distribution and serologic reactivities of HIV within the Central African Republic have not been characterized.